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Labelled glutamine and lysine analogues

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专利名称:Labelled glutamine and lysine analogues发明人:ANTHONY EAMON STOREY,MARIVI

MENDIZABAL,SUSAN CHAMPION,ALEXGIBSON,BENEDICTE GUILBERT,IAN ANDREWWILSON,PETER KNOX

申请号:AU39429申请日:19990514公开号:AU39429A公开日:19991206

摘要:Synthetic analogues of lysine and glutamine are provided which function assubstrates for the fibrin-stabilising enzyme Factor XIIIa even when labelled with adetectable moiety. The use of suitable protecting groups provides compounds whichpossess reduced susceptibility to in vivo metabolism especially by peptidases, and arehence useful agents for the diagnosis of thrombosis, embolism, atherosclerosis,inflammation or cancer.

申请人:NYCOMED AMERSHAM PLC

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