专利名称：NOVEL 12 ALPHA-HYDROXYSTEROID
DEHYDROGENASES, PRODUCTION AND USETHEREOF
发明人：AIGNER, ARNO,GROSS, RALF,SCHMID,
ROLF,BRAUN, MICHAEL,MAUER, STEFFEN
申请号：EP09724285.3申请日：20090325公开号：EP2268803A2公开日：20110105
摘要：The invention relates to 12 α-hydroxysteroid dehydrogenases, nucleic acidsequences coding for the same, expression cassettes and vectors, recombinant
microorganisms containing the corresponding coding nucleic acid sequences, a methodfor producing said 12 α-hydroxysteroid dehydrogenases, a method for enzymaticoxidation of 12 α-hydroxysteroids using said enzyme, a method for enzymatic reductionof 12-ketosteroids using said enzyme, a method for qualitative or quantitativedetermination of 12-ketosteroids and/or12α-hydroxysteroids using said 12α-hydroxysteroid dehydrogenases and a method for production of ursodesoxycholic acid,comprising the enzyme-catalysed cholic acid oxidation using said 12 α-hydroxysteroiddehydrogenases.
申请人：PHARMAZELL GMBH
地址：Rosenheimer Str. 43 83064 Raubling DE
国籍：DE
代理机构：Reitstötter - Kinzebach
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