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Methods and compositions for inhibiting the prolif

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专利名称:Methods and compositions for inhibiting the

proliferation of prostate cancer cells

发明人:Charles Y.F. Young申请号:US10567477申请日:20040804

公开号:US20070105931A1公开日:20070510

摘要:The invention provides for methods of monitoring the proliferation of culturedprostate cancer cells in the presence of celecoxib and/or nimesulide, methods of treatingan individual with prostate cancer or at risk of developing prostate cancer, and methodsof reducing the risk of recurrence of prostate cancer in an individual who had previouslybeen treated for prostate cancer. Methods of the invention further include treating anindividual with benign prostatic hyperplasia (BPH) with celecoxib and/or nimesulide aswell as methods of screening for compounds that inhibit the proliferation of prostatecancer cells. The invention provides for compositions and articles of manufacturecontaining celecoxib and/or nimesulide in particular formulations, and celecoxib and/ornimesulide with a second compound that also exerts an effect on the androgen receptor.

申请人:Charles Y.F. Young

地址:Rochester MN US

国籍:US

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