专利名称:Peptide Vaccines For Cancers Expressing
Tumor-Associated Antigens
发明人:Takuya Tsunoda,Ryuji Ohsawa,Sachiko
Yoshimura
申请号:US13744354申请日:20130117
公开号:US20130189291A1公开日:20130725
摘要:The present invention provides peptides having an amino acid sequence as setforth in SEQ ID NO: 19, 22, 30, 34, 344, 358, 41, 44, 46, 48, 78, 376, 379, 80, 100, 101, 110,111, 387, 112, 394, 114, 116, 117, 121, 395, 133, 135, 137, 426, 143, 147, 148, 149, 150, 152,153, 154, 156, 160, 161, 162, 163, 166, 174, 178, 186, 194, 196, 202, 210, 213, 214, 217, 223,227, 228, 233, 254, 271, 272 or 288, as well as peptides having the above-mentioned aminoacid sequences in which 1, 2, or several (e.g., up to 5) amino acids are substituted, deleted,or added, provided the peptides possess cytotoxic T cell inducibility. The presentinvention also provides drugs for treating or preventing a disease associated with over-expression of the CDH3, EPHA4, ECT2, HIG2, INHBB, KIF20A, KNTC2, TTK and/or URLC10,e.g. cancers containing as an active ingredient one or more of these peptides. Thepeptides of the present invention find further utility as vaccines.
申请人:Oncotherapy Science, Inc.
地址:Kanagawa JP
国籍:JP
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